A procedure called "remote ischemic preconditioning" may reduce the heart damage that occurs during coronary artery bypass surgery, cardiologists have reported in Friday's edition of The Lancet. By this procedure -- that temporarily restricts the blood flow in their arm -- patients undergoing heart bypass surgery may have improved outcomes.
Remote ischemic preconditioning works by depriving one tissue of blood flow in hopes of protecting another organ from sustained ischemia (reduced blood flow). Whether this technique actually benefits people undergoing CABG, however, is unclear.
Dr Derek M Yellon, from University College London Hospital, and colleagues studied 57 patients undergoing heart bypass surgery. Of these, 27 received remote ischemic preconditioning -- namely, three five-minute cycles of having the blood flow in one arm restricted using an automated cuff-inflator. There was a five-minute period between each cycle where the cuff was deflated. The other 30 patients served as controls.
Remote ischemic preconditioning was associated with a significant 43 percent reduction in troponin T levels after bypass surgery, the investigators report. Troponin T is a heart-related protein that may be released into the bloodstream following the "injury" to the heart during surgery. The presence of troponin T in blood in bypass surgery patients is associated with poor outcomes after surgery.
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